Project Activities
The IMIDIA consortium is organized as highly integrative and synergistic approach dividing the project into five different scientific work packages interacting as described in the figure below:
Scientific focus of IMIDIA Work Packages (WPs):
| WP1 | Beta-cell precursor and mature beta-cell lines and their use as discovery tool |
| WP2.A | Identification of novel drug targets and biomarkers: study of mouse physiological response to high fat diet and modular analysis of beta cell organization |
| WP2.B | Network for human islet procurement for experimental validation of drug targets and for genetic-genomic analysis |
| WP3 | Beta-cell life and death: identification of novel pathways and sites controlling glucose competence, proliferation and apoptosis |
| WP4 | Non-invasive imaging for in vivo diagnosing beta-cell mass and function in diabetes and following drug treatment |
| WP5 | Data repository and knowledge management |